This call aims to support the systemic transformation of regional and local industrial ecosystems toward Industry 5.0 by testing innovative approaches and incentive models. Projects should foster the adoption of human-centric technologies, strengthen organisational learning, and help close skills gaps while enhancing industrial resilience and competitiveness in the context of the green and digital transitions. Proposals must include experimentation (e.g. sandboxes), involve transdisciplinary stakeholders, and build on existing Industry 5.0 initiatives, focusing on tools, methods, and strategies that accelerate long-term transformation and talent attraction in regional industries.

Proposals are expected to contribute to the following outcomes:

• Demonstrated successful incentives for systemic transformation towards Industry 5.0 and for skills upgrading and boosting the competitiveness of EU industries.
• Development and application of Industry 5.0 enabling conditions, processes and methods for systemic transformation, organisational learning capacities and revitalisation of industries at regional/local level.
• Demonstrate / provide evidence on the implementation of Industry 5.0 innovations for better adaptation of industries to new challenges linked to twin transition (enhanced resilience), organisational agility, and contribute to tackling the skills gap / attraction of best talent in regional industrial ecosystems