This call supports the development and scaling of transformative innovations that improve accessibility, affordability, and effectiveness of health products and delivery systems, particularly for vulnerable populations and underserved markets in sub-Saharan Africa (SSA). Proposals should advance innovations beyond proof-of-concept to address unmet needs in prevention, treatment, or diagnostics for infectious diseases covered by the Global Health EDCTP3 program, focusing on patient-centered, context-specific solutions. Emphasis is placed on community engagement, regulatory pathways, local capacity building, technology transfer, and collaboration with African partners to ensure sustainable, affordable health interventions tailored to regional needs.

Expected Outcome

This topic aims at supporting activities that contribute to one or several of the expected outcomes for this call. Proposals under this topic should aim to deliver results that are contributing to at least one of the following expected outcomes:

• Generate beyond proof of concept data with innovative ideas or inventions that will improve the uptake, adherence or implementation of preventative/treatment/diagnostic solutions;
• Progress an innovative approach that makes products and services (more) accessible and affordable to commercially unattractive markets or serves vulnerable populations in SSA;
• Progress an innovative approach that addresses community-driven and trusted demand for new or repurposed tools, including those needed by hard-to-reach communities;
• Deliver innovative technologies which can generate accelerated cross-disease solutions, including communicable disease specific solutions;
• Repurpose or extend the use of an existing preventative/treatment/diagnostic intervention.